RBBP6 anticorps (AA 50-100)
Aperçu rapide pour RBBP6 anticorps (AA 50-100) (ABIN7450638)
Antigène
Voir toutes RBBP6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-100
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Fonction
- Rabbit anti-RBBP6 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 50 and 100
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
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Autre désignation
- RBBP6
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Sujet
- Background: Retinoblastoma-binding protein 6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). RBBP3 may play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53. It may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity) [taken from the Universal Protein Resource (UniProt) Q7Z6E9].
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ID gène
- 5930
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UniProt
- Q7Z6E9
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Pathways
- Regulatory RNA Pathways
Antigène
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